Penile Injection

Penile Injection — 82% of Men Would Recommend Penile Injection ED Treatment to a Friend

Intracavernosal injection therapy (ICI) is 90% effective and a highly reliable treatment for ED.  Alprostadil bi-mix (papaverine and phentolamine) and tri-mix (papaverine, phentolamine, and alprostadil) are all injectable vasodilators used to treat ED.  The customized solutions are injected into the cavernosal tissue of the penis with a very fine needle before interourse. Effective in 15 minutes and can last from 30 minutes to an hour or up to orgasm.

Self injection is learned under the guidance of the physician.

The first injection is performed in the physician’s office.  Your physician will determine the formula needed based on the erectile response from the injection.

  • First FDA-approved medication for the treatment of ED
  • 90% of men in clinical trials achieved firm erections
  • Customized dosage determined for each man
  • Works for men with a broad range of medical conditions
  • Produces a safe predictable erection

Call 800.438.8592 ext 700

Frequently Asked Questions

Is it painful?

The needle utilized for this injection is a 30 gauge ultra-fine needle.  Over 90% of patients claim that although they could feel the needle, they were surprised how painless it felt.  Also, since the needle hole is very tiny, there is very little bruising or bleeding.

How often can I use it?

The number of injections is not to exceed ten per month and we recommend that injections be spaced evenly. Also, the site of the injection should alternate between the left and right side of the penis.

Are there side effects?

First, whenever a needle is stuck into the body, a small bruise or hematoma may develop on the site of injection. A small nodule or lump may develop if the same site is injected over a long period of time. Rarely, scarring or fibrosis in the inner body of the penis may occur, or hardened area called plaque can develop at the site of injection.

The second category of side effects is produced by the medications themselves. Papaverine and Phentolamine may produce a painful, prolonged erection known as priapism. This side effect generally occurs while the doctor is attempting to adjust the dosage of medication. Once the dosage of medication is established, priapism is rare. Very often with injections, a man may develop erections lasting two to three hours. We consider priapism to be an erection lasting longer than four hours and we request that you seek medical attention immediately if this should occur. Priapism is easily reversed when treated early.

Is it effective?

The pharmacological treatment has been successful in producing an erection in over 80% of the patients in the Erectile Dysfunction Unit. This erection is more than adequate to perform intercourse. The rest of the patients in whom the injection has no effect are candidates for other forms of treatment.

Who uses this type of treatment?

A wide range of men uses the injection method to obtain erections. In general, these men are active in life and would like to remain sexually active. Men who are reluctant to have surgery find the injection method to be a good alternative to penile prosthesis. For this reason, pharmacological erections are gaining popularity.

How long have these medications been used for this purpose?

Papaverine and Phentolamine have been used for the purpose of stimulating an erection since 1983. However, Prostaglandin E1 has only been used for the past 2-3 years.

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